June 15, 2025

E303: Lisa Morales-Hellebo

Lisa Morales Hellebo is a powerhouse with 30 years of experience across tech, design, systems thinking, entrepreneurship, and now venture capital. Lisa is the Founder & Co-Managing GP of REFASHIOND Ventures, a New York–based fund investing in early-stage startups that are radically transforming industrial value chains across Data & AI, Advanced Materials, Advanced Manufacturing, and Next-Gen Logistics. It’s about reimagining what’s possible when you combine relentless curiosity with deep conviction. Whether you’re an operator, investor, or changemaker, Lisa’s vision will challenge you to think bigger — and act bolder — at the intersection of innovation and impact.

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Learn more about Lisa or follow her at:   

https://www.refashiond.com/

https://www.instagram.com/lisahellebo/

https://www.youtube.com/@refashiondventures

https://www.linkedin.com/in/supplychainlocalization/

 

Show Notes Timestamps:

0:00 Introduction to B2B Podcast

3:53 Little Lisa has been obsessed with fashion and how things are made. 👚

8:23 She was obsessed with the typography, models and the fashion of the 80s. ♻️

13:32 How she taught herself coding. 💸

18:11 You get what you need, not necessarily what you want: a pattern throughout her career and life. 🤝

22:50 Supply chain as the world’s largest operating system. 🌐

26:27 Only you are responsible for what you want to achieve and how you get there. 👷‍♀️👷‍♂️

31:57 Lisa created the first virtual personal shopper.

37:30 The misogyny was so in your face.

44:19 Disruption with follow through is action.

52:08 Supply chain as the world’s largest operating system.

56:27 Being aligned to your purpose.

 

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Lisa Morales-Hellebo Profile Photo

Founder & GP, Latina, Mom

Lisa has 30 years in tech, design and systems thinking, entrepreneurship, and community building, and has recently added VC to her list of titles as Founder & Co-Managing GP at REFASHIOND Ventures: the Industrial Transformation Fund — a NY-based venture fund that invests as the first institutional check in early-stage startups refashioning industrial value chains across Data & AI, Advanced Materials, Advanced Manufacturing, and Next Generation Logistics; defensible through economic moats.

She has always been obsessed with how things are made and pioneered mass-customization, personalization, and on-demand micromanufacturing for P&G in Silicon Valley in 1999 at a company called Reflect.com. Lisa is catalyzing the paradigm shift to localized demand chains as CEO and Founder of REFASHIOND OS (rOS), which is deploying a unified Data Layer & Control Tower across manufacturing value chains. She is also a founder of The Worldwide Supply Chain Federation, an organization that is changing how supply chain professionals learn about, collaborate, and adopt early-stage supply chain innovation around the world. Lisa is a Carnegie Mellon University alum with University Honors, Techstars alum, founded & built the New York Fashion Tech Lab, serves on the board of 3 other accelerators, has been featured in numerous publications along with 2 books, and has been the recipient of several awards; including Supply & Demand Chain Executive Magazine’s Top Woman in Supply Chain 2022, Top 100 Women in Supply Chain 2020, 2021, 2022, & 2023; and WWD’s Most Inf…