DAXXIFY vs Botox Explained: Dr. Doris Day on Neuromodulators, Fillers & Injection Fatigue
In this episode of the Facially Conscious Podcast, we’re joined by Dr. Doris Day, a board-certified dermatologist based in New York City, to discuss recent developments in neuromodulators and facial fillers—including the FDA approval of DAXXIFY, the first new Botox competitor in decades.
Dr. Day offers clear, clinical insight into how DAXXIFY compares to Botox, what makes it different, and what patients and professionals should realistically understand about its performance and longevity. From there, the conversation naturally expands into a growing topic in aesthetic medicine: filler fatigue.
Is filler fatigue a real phenomenon, or simply a misunderstood concept? We explore what happens when facial fillers are overused, how unnatural distortions can occur over time, and what dermatologists look for when prioritizing facial balance, structure, and long-term skin health.
This episode is designed to help listeners cut through speculation and trends, offering thoughtful, experience-based guidance from a trusted medical expert. Whether you’re skincare-curious, an aesthetics professional, or someone considering injectables, this conversation emphasizes education, moderation, and informed decision-making.
In this episode, we discuss:
What DAXXIFY is and how it compares to Botox
What FDA approval means for new injectable treatments
Differences among neuromodulators used in cosmetic dermatology
What “filler fatigue” refers to and how it may present over time
How overuse of dermal fillers can affect facial structure
A dermatologist’s perspective on natural-looking aesthetic outcomes
Have a question? Send us an email at info@faciallyconscious.com
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Trina Renea - Medically-trained master esthetician and celebrities’ secret weapon
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Julie Falls- Our educated consumer is here to represent you! @juliefdotcom
Dr. Vicki Rapaport -Board Certified dermatologist with practices in Beverly Hills and Culver City @rapaportdermatology and https://www.rapdermbh.com/
Rebecca Gadberry - Our resident skincare scientist and regulatory and marketing expert. @rgadberry_skincareingredients
Credits
Produced and Recorded by The Field Audio
Board-Certified Dermatologist and Founder of Day Dermatology & Aesthetics
Guest | Dr. Doris Day is a board-certified dermatologist and founder of Day Dermatology & Aesthetics in New York City. Highly sought after for her clinical expertise, she regularly lectures at national and international medical and aesthetic meetings, teaching other physicians the art and techniques of soft tissue fillers, laser treatments and facial rejuvenation with a focus on the importance of assessment and understanding the global aesthetic. In addition, she consults on product development and marketing strategies for such companies as Allergan, Galderma, Merz, L'Oreal, and P&G, where she serves on medical advisory boards and training panels to help grow their brands.
Between 2004 and 2018, Dr. Day published three books for consumers: 100 Questions and Answers About Acne (2004), Forget the Facelift: Turn Back the Clock with Dr. Day’s Revolutionary Four-Step Program for Ageless Skin (2006), and Beyond Beautiful: Using the Power of Your Mind and Aesthetic Breakthroughs to Look Naturally Young and Radiant (2018); and has hosted her own award-winning two-hour live call-in radio show for Sirius XM’s Doctor Radio since 2008.
Her specialties include laser dermatology, cosmetic dermatology, product development, and medical/broadcast journalism.
