David Letterman started out doing the very thing that scared him to death - getting up in front of strangers and trying to make them laugh. Now after wrapping up a legendary and influential career as late night host, Dave tal...
In the last decade or so, Timothy Olyphant realized that a lot of his interests when he was younger were either impractical, ill-fitting or not very cool. He found himself going in many different directions because, as he put...
Duff McKagan weathered the storm of rock and roll excess and now finds himself with a loving family, sobriety, a reunited band, and a new solo album. Duff takes Marc back to the days when he first met Axl Rose, when Guns N’ R...
Of course Lisa Kudrow talks with Marc about Friends. But first they discuss several other topics Lisa knows well, including genealogy, global migration patterns, evolutionary biology, and headaches. Lisa also explains how Jon...
A fateful moment in Kyle Mooney’s life was when his high school hip hop group went up in flames. Quite literally. All his equipment was destroyed in a fire. Lacking an outlet for his creativity, Kyle gravitated toward improv ...
If there was one constant in Anjelica Huston’s early life and career, it was the pressure to prove herself. Anjelica tells Marc about the benefits and drawbacks of being part of a Hollywood dynasty, the strains on the relatio...
Anna Konkle and Maya Erskine, co-creators and stars of the middle school-based comedy PEN15, met and bonded in college. But they knew their most authentic collaboration would come from playing themselves as adolescents, which...
Dennis Quaid believes in the benefits of familiarity. In fact, he attributes his career to it. Multiple generations of audiences know him for different films, be it Breaking Away or Dreamscape or The Parent Trap or The Rookie...
After fifty years in Hollywood producing some of the most popular movies of all time, Irwin Winkler says the question he still gets asked the most is, What does a producer do? To get the answer, Irwin tells Marc about his day...
Jane Fonda is still acting and is still an activist, two constants in her entire adult life. But as she tells Marc, Jane spent a lot of her life thinking she was a worthless person. Carrying the twin burdens of her mother’s s...
Bryan Callen always wished he could be a tough guy. Maybe it was the influence of his Marine father or maybe it was the snippets of American culture he was taking in as he grew up all over the world. Whatever it was, it cause...
Brené Brown’s degree in social work and her research into conditions like empathy and vulnerability led to one of the most viewed TED Talks of all time, millions of readers of her books, and celebrity boosters like Oprah Winf...
Mark Arm was there at the beginning of a Seattle music scene that became a national phenomenon. But all Mark ever thought he and his bandmates were doing was entertaining themselves. Mark talks about how he grew up in Suburba...
Christina Hendricks can relate if you had a lousy time in high school. Between moving around a lot to her goth fashion style and music choices to her time spent with the school theater crew, Christina was a target of bullies ...
Bruce McCulloch’s characters and disposition on The Kids in the Hall would lead you to conclude he’s somewhat shy, sensitive and kind. And while that may be true now, Bruce says he was an angry young man, a drinker, a fighter...
The last time Vincent D’Onofrio saw Marc it was at a standup show where Marc got tackled on stage by a disgruntled audience member. A lot has changed for both of them since then. You know Marc's story. But Vincent says in the...
Growing up in Texas, young Joseph Henry Burnett first experienced musical transportation while listening to records of Cole Porter and Ella Fitzgerald. He developed into not just a versatile musician and producer, but an obse...
John Lithgow can go from playing the sweetest characters you’ll ever see to truly deranged psychopaths, sometimes within the same movie. He’s good at playing kind and evil in equal measure partly because he developed his acti...
Phoebe Robinson knows too well the feeling of being “the only one.” Whether it was being the only black person in her grade, the only woman or person of color on a standup show, or the only person being asked to step out of t...
Rob Lowe had several revelations over the course of his life. One is that there’s more fun in sobriety than in being under the influence. Another is that he should have had a sex tape scandal later in life when it actually wo...
The word prodigy gets thrown around a lot, but if Tal Wilkenfeld isn’t one then the word has no meaning. Tal tells Marc how she never even saw a person play guitar until she was 14 years old. Thanks to encouragement from her ...
Amy Sedaris had no plan of action for her career other than going to Chicago to do sketch comedy and going to New York to do plays with her brother David. And as she tells Marc, she still has no plan except for doing things t...
Aidy Bryant only recently felt like she could tap into her inner rage. She remains a wonderfully nice person and hilarious performer, but with things like her new show Shrill and other mental adjustments, Aidy feels like she’...
To celebrate the milestone of 1000 episodes, Marc and WTF producer Brendan McDonald reflect on how they got here, why they created the show in the first place, and what the future holds for them and WTF. They answer listener ...