July 7, 2025

A Daily Pill for Dog Lymphoma? The Promise of Monepantel Explained | Kim Agnew, BVSc #287

A sheep dewormer shows promise in fighting dog lymphoma. Learn how Monepantel may offer hope for future dogs with cancer in this fascinating episode.

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Originally aired in 2023, Molly Jacobson interviews Dr. Kim Agnew about the groundbreaking trials of Monepantel, a sheep dewormer repurposed as a potential treatment for canine lymphoma. Discover the science behind this innovative therapy, its potential to stabilize lymphoma, and how it compares to traditional treatments like chemotherapy and prednisone.

Key Topics:

  • What is Monepantel, and how was it discovered?
  • The mechanism behind Monepantel's ability to target cancer cells.
  • Early trial results: Quality of life and stability for dogs with B-cell lymphoma.
  • How Monepantel compares to prednisone and chemotherapy.
  • Insights into ongoing and future clinical trials.
  • How dog lovers can participate in studies.

Your Voice Matters!

If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.

Related Videos:

https://www.youtube.com/watch?v=_92w6TTXM5c

https://www.youtube.com/watch?v=uAZrPM1X8ww

Related Links:

PharmAust Dog Lymphoma Clinical Trial: https://www.pharmaust.com/petdogtrial/

Chapters:

00:00 Introduction

00:30 Meet Dr. Kim Agnew and Monepantel Overview

01:15 The Origin of Monepantel: From Dewormer to Cancer Fighter

03:30 How Monepantel Targets Cancer Cells

07:00 Insights on Clinical Trials for Canine Lymphoma

09:30 Benefits of Monepantel: A Daily Pill for Dogs

12:00 Comparing Monepantel to Chemotherapy and Prednisone

14:45 Early Trial Results: Stabilizing Lymphoma in Dogs

18:30 Why Lymphoma Was Chosen for Trials

20:00 Potential for Treating Other Cancers in Dogs

23:15 How to Enroll Dogs in Clinical Trials

26:45 Side Effects and Safety of Monepantel

31:00 Future Trials and Research Goals

34:30 Closing Thoughts and Resources

33:55 Closing Remarks and Resources

Get to know Kim Agnew, BVSc:

https://www.dogcancer.com/people/kim-agnew-bvsc/

For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/

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